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Hypoxia-inducible factor-2α regulates the expression of TRAIL receptor DR5 in renal cancer cells

To understand the role of hypoxia-inducible factor (HIF)-2α in regulating sensitivity of renal cancer cells to tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis, we transfected wild-type and mutant von Hippel Lindau (VHL) proteins into TRAIL-sensitive, VHL-negative A4...

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Detalles Bibliográficos
Autores principales: Mahajan, S., Dammai, V., Hsu, T., Kraft, A.S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527645/
https://www.ncbi.nlm.nih.gov/pubmed/18544564
http://dx.doi.org/10.1093/carcin/bgn132