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The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes

BACKGROUND: Despite the considerable progress made in understanding the molecular bases of mitochondrial diseases, no effective treatments have been developed to date. Faithful animal models would be extremely helpful for designing such treatments. We showed previously that the Harlequin mouse pheno...

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Detalles Bibliográficos
Autores principales: Bénit, Paule, Goncalves, Sergio, Dassa, Emmanuel Philippe, Brière, Jean-Jacques, Rustin, Pierre
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527683/
https://www.ncbi.nlm.nih.gov/pubmed/18791645
http://dx.doi.org/10.1371/journal.pone.0003208