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The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes
BACKGROUND: Despite the considerable progress made in understanding the molecular bases of mitochondrial diseases, no effective treatments have been developed to date. Faithful animal models would be extremely helpful for designing such treatments. We showed previously that the Harlequin mouse pheno...
Autores principales: | Bénit, Paule, Goncalves, Sergio, Dassa, Emmanuel Philippe, Brière, Jean-Jacques, Rustin, Pierre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527683/ https://www.ncbi.nlm.nih.gov/pubmed/18791645 http://dx.doi.org/10.1371/journal.pone.0003208 |
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