MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells

The mucin MUC4 is a high molecular weight transmembrane glycoprotein. It consists of a mucin-type subunit (MUC4α) and a transmembrane growth factor-like subunit (MUC4β). The mucin MUC4 is overexpressed in many epithelial malignancies including ovarian cancer, suggesting a possible role in the pathog...

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Detalles Bibliográficos
Autores principales: Ponnusamy, M P, Singh, A P, Jain, M, Chakraborty, S, Moniaux, N, Batra, S K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527793/
https://www.ncbi.nlm.nih.gov/pubmed/18665193
http://dx.doi.org/10.1038/sj.bjc.6604517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527793/
https://www.ncbi.nlm.nih.gov/pubmed/18665193
http://dx.doi.org/10.1038/sj.bjc.6604517

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