Reciprocal relationship between expression of hypoxia inducible factor 1α (HIF-1α) and the pro-apoptotic protein Bid in ex vivo colorectal cancer

Hypoxia inducible factor 1 (HIF-1) represses the transcription of pro-apoptotic bid in colorectal cancer cells in vitro. To assess the clinical relevance of this observation, HIF-1α and Bid were assessed in serial sections of 39 human colorectal adenocarcinomas by immunohistochemistry. In high HIF-1...

Descripción completa

Detalles Bibliográficos
Autores principales: Seenath, M M, Roberts, D, Cawthorne, C, Saunders, M P, Armstrong, G R, O'Dwyer, S T, Stratford, I J, Dive, C, Renehan, A G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527799/
https://www.ncbi.nlm.nih.gov/pubmed/18648372
http://dx.doi.org/10.1038/sj.bjc.6604474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527799/
https://www.ncbi.nlm.nih.gov/pubmed/18648372
http://dx.doi.org/10.1038/sj.bjc.6604474

Ejemplares similares