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Prostaglandin E(2) stimulates Fas ligand expression via the EP1 receptor in colon cancer cells

Fas ligand (FasL/CD95L) is a member of the tumour necrosis factor superfamily that triggers apoptosis following crosslinking of the Fas receptor. Despite studies strongly implicating tumour-expressed FasL as a major inhibitor of the anti-tumour immune response, little is known about the mechanisms t...

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Detalles Bibliográficos
Autores principales: O'Callaghan, G, Kelly, J, Shanahan, F, Houston, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527805/
https://www.ncbi.nlm.nih.gov/pubmed/18648368
http://dx.doi.org/10.1038/sj.bjc.6604490