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Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells

RECK is a novel tumour suppressor gene that negatively regulates matrix metalloproteinases (MMPs) and inhibits tumour invasion, angiogenesis and metastasis. In the present study, we investigated the effects of epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, on the methylation sta...

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Detalles Bibliográficos
Autores principales: Kato, K, Long, N K, Makita, H, Toida, M, Yamashita, T, Hatakeyama, D, Hara, A, Mori, H, Shibata, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527823/
https://www.ncbi.nlm.nih.gov/pubmed/18665171
http://dx.doi.org/10.1038/sj.bjc.6604521