MT1-MMP regulates urothelial cell invasion via transcriptional regulation of Dickkopf-3

Membrane type-1 matrix metalloproteinase (MT1-MMP) is a zinc-binding endopeptidase, which plays a crucial role in tumour growth, invasion and metastasis. We have shown previously that MT1-MMP has higher expression levels in the human urothelial cell carcinoma (UCC) tissue. We show here that siRNA ag...

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Detalles Bibliográficos
Autores principales: Saeb-Parsy, K, Veerakumarasivam, A, Wallard, M J, Thorne, N, Kawano, Y, Murphy, G, Neal, D E, Mills, I G, Kelly, J D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527828/
https://www.ncbi.nlm.nih.gov/pubmed/18665176
http://dx.doi.org/10.1038/sj.bjc.6604513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527828/
https://www.ncbi.nlm.nih.gov/pubmed/18665176
http://dx.doi.org/10.1038/sj.bjc.6604513

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