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A role for topoisomerase IIα in the formation of radiation-induced chromatid breaks

Chromatid breaks in cells exposed to low dose irradiation are thought to be initiated by DNA double-strand breaks (DSB), and the frequency of chromatid breaks has been shown to increase in DSB rejoining deficient cells. However, the underlying causes of the wide variation in frequencies of G2 chroma...

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Detalles Bibliográficos
Autores principales: Terry, S Y A, Riches, A C, Bryant, P E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527830/
https://www.ncbi.nlm.nih.gov/pubmed/18665175
http://dx.doi.org/10.1038/sj.bjc.6604514