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A role for topoisomerase IIα in the formation of radiation-induced chromatid breaks
Chromatid breaks in cells exposed to low dose irradiation are thought to be initiated by DNA double-strand breaks (DSB), and the frequency of chromatid breaks has been shown to increase in DSB rejoining deficient cells. However, the underlying causes of the wide variation in frequencies of G2 chroma...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527830/ https://www.ncbi.nlm.nih.gov/pubmed/18665175 http://dx.doi.org/10.1038/sj.bjc.6604514 |