Fractionated (131)I anti-CEA radioimmunotherapy: effects on xenograft tumour growth and haematological toxicity in mice

Dose fractionation has been proposed as a method to improve the therapeutic ratio of radioimmunotherapy (RIT). This study compared a single administration of 7.4 MBq (131)I-anti-CEA antibody given on day 1 with the same total activity given as fractionated treatment: 3.7 MBq (days 1 and 3), 2.4 MBq...

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Detalles Bibliográficos
Autores principales: Violet, J A, Dearling, J L J, Green, A J, Begent, R H J, Pedley, R B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527834/
https://www.ncbi.nlm.nih.gov/pubmed/18682714
http://dx.doi.org/10.1038/sj.bjc.6604511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527834/
https://www.ncbi.nlm.nih.gov/pubmed/18682714
http://dx.doi.org/10.1038/sj.bjc.6604511

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