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IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms

BACKGROUND: IL-21, a member of the common γ-chain utilizing family of cytokines, participates in immune and inflammatory processes. In addition, the cytokine has been linked to autoimmunity in humans and rodents. METHODOLOGY/PRINCIPAL FINDINGS: To investigate the mechanism whereby IL-21 affects the...

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Detalles Bibliográficos
Autores principales: Datta, Shrimati, Sarvetnick, Nora E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527999/
https://www.ncbi.nlm.nih.gov/pubmed/18773086
http://dx.doi.org/10.1371/journal.pone.0003118