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Identification of Chromatin Remodeling Genes Arid4a and Arid4b as Leukemia Suppressor Genes

BACKGROUND: Leukemia evolves through a multistep process from premalignancy to malignancy. Epigenetic alterations, including histone modifications, have been proposed to play an important role in tumorigenesis. The involvement of two chromatin remodeling genes, retinoblastoma-binding protein 1 (Rbbp...

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Detalles Bibliográficos
Autores principales: Wu, Mei-Yi, Eldin, Karen W., Beaudet, Arthur L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528019/
https://www.ncbi.nlm.nih.gov/pubmed/18728284
http://dx.doi.org/10.1093/jnci/djn253