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Identification of Chromatin Remodeling Genes Arid4a and Arid4b as Leukemia Suppressor Genes
BACKGROUND: Leukemia evolves through a multistep process from premalignancy to malignancy. Epigenetic alterations, including histone modifications, have been proposed to play an important role in tumorigenesis. The involvement of two chromatin remodeling genes, retinoblastoma-binding protein 1 (Rbbp...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528019/ https://www.ncbi.nlm.nih.gov/pubmed/18728284 http://dx.doi.org/10.1093/jnci/djn253 |