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Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies

After internalization, ubiquitinated signaling receptors are delivered to early endosomes. There, they are sorted and incorporated into the intralumenal invaginations of nascent multivesicular bodies, which function as transport intermediates to late endosomes. Receptor sorting is achieved by Hrs—an...

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Detalles Bibliográficos
Autores principales: Pons, Véronique, Luyet, Pierre-Philippe, Morel, Etienne, Abrami, Laurence, van der Goot, F. Gisou, Parton, Robert G, Gruenberg, Jean
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528051/
https://www.ncbi.nlm.nih.gov/pubmed/18767904
http://dx.doi.org/10.1371/journal.pbio.0060214