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Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies
After internalization, ubiquitinated signaling receptors are delivered to early endosomes. There, they are sorted and incorporated into the intralumenal invaginations of nascent multivesicular bodies, which function as transport intermediates to late endosomes. Receptor sorting is achieved by Hrs—an...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528051/ https://www.ncbi.nlm.nih.gov/pubmed/18767904 http://dx.doi.org/10.1371/journal.pbio.0060214 |