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Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease

Gains of chromosomes 7p and 8q are associated with poor prognosis among oestrogen receptor-positive (ER+) stage I/II breast cancer. To identify transcriptional changes associated with this breast cancer subtype, we applied suppression subtractive hybridisation method to analyse differentially expres...

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Detalles Bibliográficos
Autores principales: Helms, M W, Kemming, D, Pospisil, H, Vogt, U, Buerger, H, Korsching, E, Liedtke, C, Schlotter, C M, Wang, A, Chan, S Y, Brandt, B H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528137/
https://www.ncbi.nlm.nih.gov/pubmed/18728668
http://dx.doi.org/10.1038/sj.bjc.6604556