Multimolecular complex of Par-4 and E2F1 binding to Smac promoter contributes to glutamate-induced apoptosis in human- bone mesenchymal stem cells

Neural cells undergo glutamate-induced apoptosis in ischaemic brain tissue, in which prostate apoptosis response-4 gene (Par-4) is involved. Human-bone mesenchymal stem cells can be utilized as an effective therapy for ischemic brain injury. In this study, we found that glutamate could induce apopto...

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Detalles Bibliográficos
Autores principales: Lu, Chao, Chen, Jie-Qing, Zhou, Guo-Ping, Wu, Sheng-Hua, Guan, Ya-Fei, Yuan, Chuan-Shun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528162/
https://www.ncbi.nlm.nih.gov/pubmed/18660514
http://dx.doi.org/10.1093/nar/gkn426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528162/
https://www.ncbi.nlm.nih.gov/pubmed/18660514
http://dx.doi.org/10.1093/nar/gkn426

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