A functional selection of viral genetic elements in cultured cells to identify hepatitis C virus RNA translation inhibitors(†)

We developed a functional selection system based on randomized genetic elements (GE) to identify potential regulators of hepatitis C virus (HCV) RNA translation, a process initiated by an internal ribosomal entry site (IRES). A retroviral HCV GE library was introduced into HepG2 cells, stably expres...

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Detalles Bibliográficos
Autores principales: Jaffrelo, Loic, Chabas, Sandrine, Reigadas, Sandrine, Pflieger, Aude, Wychowski, Czeslaw, Rumi, Julie, Ventura, Michel, Toulmé, Jean-Jacques, Staedel, Cathy
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528164/
https://www.ncbi.nlm.nih.gov/pubmed/18614605
http://dx.doi.org/10.1093/nar/gkn427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528164/
https://www.ncbi.nlm.nih.gov/pubmed/18614605
http://dx.doi.org/10.1093/nar/gkn427

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