Cargando…

Molecular dynamics of a κB DNA element: base flipping via cross-strand intercalative stacking in a microsecond-scale simulation

The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target regulatory elements. To better understand DNA structure, function, and dynamics in general, and prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Mura, Cameron, McCammon, J. Andrew
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528173/
https://www.ncbi.nlm.nih.gov/pubmed/18653524
http://dx.doi.org/10.1093/nar/gkn473