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Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation
C-Met, the receptor of hepatocyte growth factor (HGF), through overexpression or mutation, is a major protooncogene that provides an attractive molecular target for cancer therapy. HGF/c-Met–induced tumorigenesis is dependent, in part, on the transcription factor and oncogene signal transducer and a...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528569/ https://www.ncbi.nlm.nih.gov/pubmed/18779368 http://dx.doi.org/10.1083/jcb.200806076 |