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To flip or not to flip: lipid–protein charge interactions are a determinant of final membrane protein topology

The molecular details of how lipids influence final topological organization of membrane proteins are not well understood. Here, we present evidence that final topology is influenced by lipid–protein interactions most likely outside of the translocon. The N-terminal half of Escherichia coli lactose...

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Detalles Bibliográficos
Autores principales: Bogdanov, Mikhail, Xie, Jun, Heacock, Phil, Dowhan, William
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528571/
https://www.ncbi.nlm.nih.gov/pubmed/18779371
http://dx.doi.org/10.1083/jcb.200803097