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Survival of the weakest: signaling aided by endosomes

The tyrosine kinase receptor c-Met plays a key role in cell proliferation, morphogenesis, and motility in response to hepatocyte growth factor. C-Met is often altered in cancer and is a major target for therapeutic intervention. Despite knowing a great deal of the molecular machinery downstream of t...

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Detalles Bibliográficos
Autores principales: McShane, Marisa P., Zerial, Marino
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528579/
https://www.ncbi.nlm.nih.gov/pubmed/18779366
http://dx.doi.org/10.1083/jcb.200807165