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Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation

The low-density lipoprotein receptor–related proteins 5 and 6 (LRP5/6) are coreceptors for Frizzled and transmit signals from the plasma membrane to the cytosol. However, the mechanism for LRP5/6 signal transmission remains undefined. Here, we identify cytoplasmic activation/proliferation-associated...

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Detalles Bibliográficos
Autores principales: Ding, Yu, Xi, Ying, Chen, Ting, Wang, Ji-yong, Tao, Dong-lei, Wu, Zhi-Li, Li, Yi-ping, Li, Chen, Zeng, Rong, Li, Lin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528581/
https://www.ncbi.nlm.nih.gov/pubmed/18762581
http://dx.doi.org/10.1083/jcb.200803147