IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop

IGF-II stimulates both mitogenesis and myogenesis through its binding and activation of the IGF-I receptor (IGF-IR). How this growth factor pathway promotes these two opposite cellular responses is not well understood. We investigate whether local IGF binding protein-5 (IGFBP-5) promotes the myogeni...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Hongxia, Yin, Ping, Duan, Cunming
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528583/
https://www.ncbi.nlm.nih.gov/pubmed/18762576
http://dx.doi.org/10.1083/jcb.200712110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528583/
https://www.ncbi.nlm.nih.gov/pubmed/18762576
http://dx.doi.org/10.1083/jcb.200712110

Ejemplares similares