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ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65

Directed cell migration requires the orientation of the Golgi and centrosome toward the leading edge. We show that stimulation of interphase cells with the mitogens epidermal growth factor or lysophosphatidic acid activates the extracellular signal–regulated kinase (ERK), which phosphorylates the Go...

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Detalles Bibliográficos
Autores principales: Bisel, Blaine, Wang, Yanzhuang, Wei, Jen-Hsuan, Xiang, Yi, Tang, Danming, Miron-Mendoza, Miguel, Yoshimura, Shin-ichiro, Nakamura, Nobuhiro, Seemann, Joachim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528584/
https://www.ncbi.nlm.nih.gov/pubmed/18762583
http://dx.doi.org/10.1083/jcb.200805045