Amyloid Oligomer Conformation in a Group of Natively Folded Proteins

Recent in vitro and in vivo studies suggest that destabilized proteins with defective folding induce aggregation and toxicity in protein-misfolding diseases. One such unstable protein state is called amyloid oligomer, a precursor of fully aggregated forms of amyloid. Detection of various amyloid oli...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshiike, Yuji, Minai, Ryoichi, Matsuo, Yo, Chen, Yun-Ru, Kimura, Tetsuya, Takashima, Akihiko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528939/
https://www.ncbi.nlm.nih.gov/pubmed/18800165
http://dx.doi.org/10.1371/journal.pone.0003235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528939/
https://www.ncbi.nlm.nih.gov/pubmed/18800165
http://dx.doi.org/10.1371/journal.pone.0003235

Ejemplares similares