A Drosophila Model for Amyotrophic Lateral Sclerosis Reveals Motor Neuron Damage by Human SOD1

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease that leads to loss of motor function and early death. About 5% of cases are inherited, with the majority of identified linkages in the gene encoding copper, zinc-superoxide dismutase (SOD1). Strong evidence indicates that the SOD1 mutatio...

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Detalles Bibliográficos
Autores principales: Watson, Melanie R., Lagow, Robert D., Xu, Kexiang, Zhang, Bing, Bonini, Nancy M.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Molecular Basis of Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529125/
https://www.ncbi.nlm.nih.gov/pubmed/18596033
http://dx.doi.org/10.1074/jbc.M804817200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529125/
https://www.ncbi.nlm.nih.gov/pubmed/18596033
http://dx.doi.org/10.1074/jbc.M804817200

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