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Combinatorial Signals of Activin/Nodal and Bone Morphogenic Protein Regulate the Early Lineage Segregation of Human Embryonic Stem Cells

Cell fate commitment of pre-implantation blastocysts, to either the inner cell mass or trophoblast, is the first step in cell lineage segregation of the developing human embryo. However, the intercellular signals that control fate determination of these cells remain obscure. Human embryonic stem cel...

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Detalles Bibliográficos
Autores principales: Wu, Zhao, Zhang, Wei, Chen, Guibin, Cheng, Lu, Liao, Jing, Jia, Nannan, Gao, Yuan, Dai, Huiming, Yuan, Jinduo, Cheng, Linzhao, Xiao, Lei
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529127/
https://www.ncbi.nlm.nih.gov/pubmed/18596037
http://dx.doi.org/10.1074/jbc.M803893200