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Critical role for BIM in T cell receptor restimulation-induced death

BACKGROUND: Upon repeated or chronic antigen stimulation, activated T cells undergo a T cell receptor (TCR)-triggered propriocidal cell death important for governing the intensity of immune responses. This is thought to be chiefly mediated by an extrinsic signal through the Fas-FasL pathway. However...

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Detalles Bibliográficos
Autores principales: Snow, Andrew L, Oliveira, João B, Zheng, Lixin, Dale, Janet K, Fleisher, Thomas A, Lenardo, Michael J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529272/
https://www.ncbi.nlm.nih.gov/pubmed/18715501
http://dx.doi.org/10.1186/1745-6150-3-34