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MicroRNAs can regulate human APP levels

A number of studies have shown that increased APP levels, resulting from either a genomic locus duplication or alteration in APP regulatory sequences, can lead to development of early-onset dementias, including Alzheimer's disease (AD). Therefore, understanding how APP levels are regulated coul...

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Detalles Bibliográficos
Autores principales: Patel, Neha, Hoang, David, Miller, Nathan, Ansaloni, Sara, Huang, Qihong, Rogers, Jack T, Lee, Jeremy C, Saunders, Aleister J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529281/
https://www.ncbi.nlm.nih.gov/pubmed/18684319
http://dx.doi.org/10.1186/1750-1326-3-10