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An amphioxus orthologue of the estrogen receptor that does not bind estradiol: Insights into estrogen receptor evolution
BACKGROUND: The origin of nuclear receptors (NRs) and the question whether the ancestral NR was a liganded or an unliganded transcription factor has been recently debated. To obtain insight into the evolution of the ligand binding ability of estrogen receptors (ER), we comparatively characterized th...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529310/ https://www.ncbi.nlm.nih.gov/pubmed/18655705 http://dx.doi.org/10.1186/1471-2148-8-219 |