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Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores
BACKGROUND: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic data. Two statistical models have been proposed. In the asymptotic limit of long sequences, the Karlin-Altschul model is b...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529321/ https://www.ncbi.nlm.nih.gov/pubmed/18687111 http://dx.doi.org/10.1186/1471-2105-9-332 |