Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy

BACKGROUND: The membrane transporters such as P-glycoprotein (Pgp), the MDR1 gene product, are one of causes of treatment failure in cancer patients. In this study, the epigenetic mechanisms involved in differential MDR1 mRNA expression were compared between 10 gastric and 9 colon cancer cell lines....

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Detalles Bibliográficos
Autores principales: Lee, Tae-Bum, Park, Jung-Hee, Min, Young-Don, Kim, Kyung-Jong, Choi, Cheol-Hee
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529328/
https://www.ncbi.nlm.nih.gov/pubmed/18673531
http://dx.doi.org/10.1186/1471-230X-8-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529328/
https://www.ncbi.nlm.nih.gov/pubmed/18673531
http://dx.doi.org/10.1186/1471-230X-8-33

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