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A Recoding Method to Improve the Humoral Immune Response to an HIV DNA Vaccine

This manuscript describes a novel strategy to improve HIV DNA vaccine design. Employing a new information theory based bioinformatic algorithm, we identify a set of nucleotide motifs which are common in the coding region of HIV, but are under-represented in genes that are highly expressed in the hum...

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Detalles Bibliográficos
Autores principales: Huang, Yaoxing, Krasnitz, Michael, Rabadan, Raul, Witten, Daniela M., Song, Yang, Levine, Arnold J., Ho, David D., Robins, Harlan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529374/
https://www.ncbi.nlm.nih.gov/pubmed/18791646
http://dx.doi.org/10.1371/journal.pone.0003214