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A Recoding Method to Improve the Humoral Immune Response to an HIV DNA Vaccine
This manuscript describes a novel strategy to improve HIV DNA vaccine design. Employing a new information theory based bioinformatic algorithm, we identify a set of nucleotide motifs which are common in the coding region of HIV, but are under-represented in genes that are highly expressed in the hum...
Autores principales: | Huang, Yaoxing, Krasnitz, Michael, Rabadan, Raul, Witten, Daniela M., Song, Yang, Levine, Arnold J., Ho, David D., Robins, Harlan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529374/ https://www.ncbi.nlm.nih.gov/pubmed/18791646 http://dx.doi.org/10.1371/journal.pone.0003214 |
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