Kaposi's Sarcoma-Associated Herpesvirus K7 Induces Viral G Protein-Coupled Receptor Degradation and Reduces Its Tumorigenicity

The Kaposi's sarcoma-associated herpesvirus (KSHV) genome encodes a G protein-coupled receptor (vGPCR). vGPCR is a ligand-independent, constitutively active signaling molecule that promotes cell growth and proliferation; however, it is not clear how vGPCR is negatively regulated. We report here...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Dong, Xiaonan, Negaard, Ashley, Feng, Pinghui
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529400/
https://www.ncbi.nlm.nih.gov/pubmed/18802460
http://dx.doi.org/10.1371/journal.ppat.1000157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529400/
https://www.ncbi.nlm.nih.gov/pubmed/18802460
http://dx.doi.org/10.1371/journal.ppat.1000157

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