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Screening and Replication using the Same Data Set: Testing Strategies for Family-Based Studies in which All Probands Are Affected
For genome-wide association studies in family-based designs, we propose a powerful two-stage testing strategy that can be applied in situations in which parent-offspring trio data are available and all offspring are affected with the trait or disease under study. In the first step of the testing str...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529406/ https://www.ncbi.nlm.nih.gov/pubmed/18802462 http://dx.doi.org/10.1371/journal.pgen.1000197 |