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Essential contribution of CCL3 to alkali-induced corneal neovascularization by regulating vascular endothelial growth factor production by macrophages

PURPOSE: To evaluate the roles of CCL3 and its specific chemokine receptors, CCR1 and CCR5, in alkali-induced corneal neovascularization (CNV). METHODS: Chemical denudation of corneal and limbal epithelium was performed on wild-type (WT) BALB/c mice and CCL3-, CCR1-, and CCR5-deficienct (knockout [K...

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Detalles Bibliográficos
Autores principales: Lu, Peirong, Li, Longbiao, Wu, Yu, Mukaida, Naofumi, Zhang, Xueguang
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529469/
https://www.ncbi.nlm.nih.gov/pubmed/18776949