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Identification of candidate genes for human retinal degeneration loci using differentially expressed genes from mouse photoreceptor dystrophy models

PURPOSE: Retinal degeneration (RD) is a complex mechanism that appears to involve many biologic processes including oxidative stress, apoptosis, and cellular remodeling. Currently there are 51 mapped, but not identified, RD human disease loci. METHODS: To assign possible disease genes to RD loci, we...

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Detalles Bibliográficos
Autores principales: Demos, Christina, Bandyopadhyay, Mausumi, Rohrer, Bärbel
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529471/
https://www.ncbi.nlm.nih.gov/pubmed/18776951