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An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma

BACKGROUND: The role of microRNAs (miRNAs) in multiple myeloma (MM) has yet to be fully elucidated. To identify miRNAs that are potentially deregulated in MM, we investigated those mapping within transcription units, based on evidence that intronic miRNAs are frequently coexpressed with their host g...

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Detalles Bibliográficos
Autores principales: Ronchetti, Domenica, Lionetti, Marta, Mosca, Laura, Agnelli, Luca, Andronache, Adrian, Fabris, Sonia, Deliliers, Giorgio Lambertenghi, Neri, Antonino
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531129/
https://www.ncbi.nlm.nih.gov/pubmed/18700954
http://dx.doi.org/10.1186/1755-8794-1-37