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HLA-C increases HIV-1 infectivity and is associated with gp120
BACKGROUND: A recently identified genetic polymorphism located in the 5' region of the HLA-C gene is associated with individual variations in HIV-1 viral load and with differences in HLA-C expression levels. HLA-C has the potential to restrict HIV-1 by presenting epitopes to cytotoxic T cells b...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531131/ https://www.ncbi.nlm.nih.gov/pubmed/18673537 http://dx.doi.org/10.1186/1742-4690-5-68 |