HLA-C increases HIV-1 infectivity and is associated with gp120

BACKGROUND: A recently identified genetic polymorphism located in the 5' region of the HLA-C gene is associated with individual variations in HIV-1 viral load and with differences in HLA-C expression levels. HLA-C has the potential to restrict HIV-1 by presenting epitopes to cytotoxic T cells b...

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Detalles Bibliográficos
Autores principales: Matucci, Andrea, Rossolillo, Paola, Baroni, Miriam, Siccardi, Antonio G, Beretta, Alberto, Zipeto, Donato
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531131/
https://www.ncbi.nlm.nih.gov/pubmed/18673537
http://dx.doi.org/10.1186/1742-4690-5-68

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