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Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements

BACKGROUND: APOBEC3 cytosine deaminases have been demonstrated to restrict infectivity of a series of retroviruses, with different efficiencies depending on the retrovirus. In addition, APOBEC3 proteins can severely restrict the intracellular transposition of a series of retroelements with a strictl...

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Detalles Bibliográficos
Autores principales: Esnault, Cécile, Priet, Stéphane, Ribet, David, Heidmann, Odile, Heidmann, Thierry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531183/
https://www.ncbi.nlm.nih.gov/pubmed/18702815
http://dx.doi.org/10.1186/1742-4690-5-75