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Interactions between branched DNAs and peptide inhibitors of DNA repair

The RecG helicase of Escherichia coli unwinds both Holliday junction (HJ) and replication fork DNA substrates. Our lab previously identified and characterized peptides (WRWYCR and KWWCRW) that block the activity of RecG on these substrates. We determined that the peptides bind HJ DNA and prevent the...

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Detalles Bibliográficos
Autores principales: Kepple, Kevin V., Patel, Namita, Salamon, Peter, Segall, Anca M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532710/
https://www.ncbi.nlm.nih.gov/pubmed/18689438
http://dx.doi.org/10.1093/nar/gkn512