Intragenic suppressors of temperature-sensitive rne mutations lead to the dissociation of RNase E activity on mRNA and tRNA substrates in Escherichia coli

RNase E of Escherichia coli is an essential endoribonuclease that is involved in many aspects of RNA metabolism. Point mutations in the S1 RNA-binding domain of RNase E (rne-1 and rne-3071) lead to temperature-sensitive growth along with defects in 5S rRNA processing, mRNA decay and tRNA maturation....

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Detalles Bibliográficos
Autores principales: Perwez, Tariq, Hami, Danyal, Maples, Valerie F., Min, Zhao, Wang, Bi-Cheng, Kushner, Sidney R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532720/
https://www.ncbi.nlm.nih.gov/pubmed/18689439
http://dx.doi.org/10.1093/nar/gkn476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532720/
https://www.ncbi.nlm.nih.gov/pubmed/18689439
http://dx.doi.org/10.1093/nar/gkn476

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