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Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax

The apoptosis stimulating p53 proteins, ASPP1 and ASPP2, are the first two common activators of the p53 protein family that selectively enable the latter to regulate specific apoptotic target genes, which facilitates yes yet unknown mechanisms for discrimination between cell cycle arrest and apoptos...

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Detalles Bibliográficos
Autores principales: Patel, Seema, George, Roger, Autore, Flavia, Fraternali, Franca, Ladbury, John E., Nikolova, Penka V.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532732/
https://www.ncbi.nlm.nih.gov/pubmed/18676979
http://dx.doi.org/10.1093/nar/gkn490