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Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch
Applications of conditional gene expression, whether for therapeutic or basic research purposes, are increasingly requiring mammalian gene control systems that exhibit far tighter control properties. While numerous approaches have been used to improve the widely used Tet-regulatory system, many appl...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532736/ https://www.ncbi.nlm.nih.gov/pubmed/18632760 http://dx.doi.org/10.1093/nar/gkn443 |