Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

Mitochondria form a highly dynamic tubular network, the morphology of which is regulated by frequent fission and fusion events. However, the role of mitochondrial fission in homeostasis of the organelle is still unknown. Here we report that preventing mitochondrial fission, by down-regulating expres...

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Detalles Bibliográficos
Autores principales: Parone, Philippe A., Da Cruz, Sandrine, Tondera, Daniel, Mattenberger, Yves, James, Dominic I., Maechler, Pierre, Barja, François, Martinou, Jean-Claude
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532749/
https://www.ncbi.nlm.nih.gov/pubmed/18806874
http://dx.doi.org/10.1371/journal.pone.0003257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532749/
https://www.ncbi.nlm.nih.gov/pubmed/18806874
http://dx.doi.org/10.1371/journal.pone.0003257

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