Cargando…
Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
Mitochondria form a highly dynamic tubular network, the morphology of which is regulated by frequent fission and fusion events. However, the role of mitochondrial fission in homeostasis of the organelle is still unknown. Here we report that preventing mitochondrial fission, by down-regulating expres...
Autores principales: | Parone, Philippe A., Da Cruz, Sandrine, Tondera, Daniel, Mattenberger, Yves, James, Dominic I., Maechler, Pierre, Barja, François, Martinou, Jean-Claude |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532749/ https://www.ncbi.nlm.nih.gov/pubmed/18806874 http://dx.doi.org/10.1371/journal.pone.0003257 |
Ejemplares similares
-
Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli
por: Arnoult, Damien, et al.
Publicado: (2002) -
Mitochondrial dynamics: quantifying mitochondrial fusion in vitro
por: Jourdain, Alexis, et al.
Publicado: (2010) -
Mitochondrial RNA granules: Compartmentalizing mitochondrial gene expression
por: Jourdain, Alexis A., et al.
Publicado: (2016) -
Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1
por: Ehses, Sarah, et al.
Publicado: (2009) -
Mitochondrial fission factor (MFF) frameshift variant in Bullmastiffs with mitochondrial fission encephalopathy
por: Christen, Matthias, et al.
Publicado: (2022)