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Systematic Structure-Activity Analysis of Microcin J25

Microcin J25 (MccJ25) is a 21-residue plasmid-encoded ribosomally synthesized lariat-protoknot antibacterial peptide that targets bacterial RNA polymerase. MccJ25 consists of an 8-residue cycle followed by a 13-residue tail that loops back and threads through the cycle. We have performed systematic...

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Detalles Bibliográficos
Autores principales: Pavlova, Olga, Mukhopadhyay, Jayanta, Sineva, Elena, Ebright, Richard H., Severinov, Konstantin
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533079/
https://www.ncbi.nlm.nih.gov/pubmed/18632663
http://dx.doi.org/10.1074/jbc.M803995200